Neuromuscular correlates of subthalamic stimulation and upper limb freezing in Parkinson’s disease
详细信息 查看全文
- 作者：Marlieke Scholtena ; b ; c ; d ; marlieke.scholten@uni-tuebingen.de" class="auth_mail" title="E-mail the corresponding author ; Rosa Klotza ; b ; c ; Christian Plewniac ; f ; Tobias Wä ; chtere ; Carina Mielkea ; b ; c ; Bastiaan R. Bloemg ; Christoph Braunc ; h ; i ; Ulf Ziemannc ; j ; Rathinaswamy B. Govindank ; Alireza Gharabaghic ; l ; Rejko Krü ; gera ; b ; c ; m ; Daniel Weissa ; b ; c ; daniel.weiss@uni-tuebingen.de" class="auth_mail" title="E-mail the corresponding author
- 关键词：ED ; extensor digitorum communis muscle ; EEG ; electroencephalography ; EMG ; electromyography ; FD ; flexor digitorum superficialis muscle ; iPD ; idiopathic Parkinson&rsquo ; s disease ; SM1 ; primary sensorimotor area ; StimOff ; deep brain stimulation turned off ; StimOn ; deep brain stimulation turned on ; STN-DBS ; deep brain stimulation of the subthalamic nucleus ; ULF ; upper limb freezing ; UPDRS ; Unified Parkinson&rsquo ; s Disease Rating Scale
- 刊名：Clinical Neurophysiology
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：127
- 期：1
- 页码：610-620
- 全文大小：1391 K
文摘
- •
Subthalamic stimulation reduces exaggerated low-frequency intermuscular coherence during continuous fingertapping in iPD.
- •
We implemented criteria to detect and segment freezing events of upper limb movement for electrophysiological data analyses.
- •
Freezing of upper limb movement presents with increased low-frequency muscular and cortical activation, likely reflecting increased cortical motor inhibition.