Vitamin E: Emerging aspects and new directions

详细信息    查看全文

• 作者：Francesco Galli^a ; ¹ ; ^{francesco.galli@unipg.it} ; Angelo Azzi^b ; ¹ ; ^{angelo.azzi@tufts.edu} ; Marc Birringer^c ; ¹ ; ^{marc.birringer@oe.hs-fulda.de} ; Joan M. Cook-Mills^d ; ¹ ; ^{j-cook-mills@northwestern.edu} ; Manfred Eggersdorfer^e ; ¹ ; ^{manfred.eggersdorfer@dsm.com} ; Jan Frank^f ; ¹ ; ^{jan.frank@nutres.de} ; Gabriele Cruciani^g ; ¹ ; ^{gabriele.cruciani@unipg.it} ; Stefan Lorkowski^h ; ⁱ ; ¹ ; ^{stefan.lorkowski@uni-jena.de} ; Nesrin Kartal Ö ; zer^j ; ¹ ; ^{nkozer@marmara.edu.tr}
• 关键词：Vitamin E ; Tocopherols ; Tocotrienols ; Cytochrome P-450 ; Antioxidants ; Long-chain metabolites ; Tocopheryl phosphate ; Nutrition ; NASH
• 刊名：Free Radical Biology and Medicine
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：102
• 期：Complete
• 页码：16-36
• 全文大小：994 K
• 卷排序：102

文摘

Biological functions and the essentiality of vitamin E for human health are still questionable. RDA and AI values have been proposed, but the concept of optimal intake for this vitamin remains elusive. In the last decades physiological and bioactive metabolites of vitamin E have been identified. Recent studies reveal promising applications of vitamin E in prevention of chronic diseases such as cardiovascular disease and NASH. Other potential applications of vitamin E have been proposed in neuroprotection, immunomodulation and antiallergic interventions.