Periventricular Leukomalacia is Decreasing in Japan

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• 作者：Tokio Sugiura ; MD ; PhD^a ; ^{tokio@med.nagoya-cu.ac.jp} ; Tatenobu Goto ; MD ; PhD^a ; Hiroko Ueda ; MD^a ; Koichi Ito ; MD ; PhD^a ; Hiroki Kakita ; MD ; PhD^a ; Rika Nagasaki ; MD^a ; Keisuke Mizuno ; MD ; PhD^b ; Satoshi Suzuki ; MD ; PhD^c ; Ineko Kato ; MD ; PhD^a ; Hajime Togari ; MD ; PhD^a
• 刊名：Pediatric Neurology
• 出版年：2012
• 出版时间：July, 2012
• 年：2012
• 卷：47
• 期：1
• 页码：35-39
• 全文大小：154 K

文摘

Periventricular leukomalacia is recognized as the leading cause of cerebral palsy in preterm infants. To clarify the prevalence of periventricular leukomalacia and cerebral palsy in Japan, a nationwide survey was performed. The prevalence of periventricular leukomalacia in the group of surviving preterm infants of gestational ages less than 33 weeks born in 2007 was 2.7 % (78/2883) on ultrasound diagnosis, and 3.3 % (92/2824) on magnetic resonance imaging. The prevalence of cerebral palsy was 4.3 % (125/2883) on clinical diagnosis. In our previous study, the prevalences of periventricular leukomalacia in 1990-1991, 1993-1994, 1996, and 1999 were 4.8 % , 4.9 % , 4.9 % , and 5.3 % on ultrasound, and 7.9 % , 7.7 % , 6.9 % , and 7.3 % on magnetic resonance imaging, respectively. The prevalence of periventricular leukomalacia has decreased significantly in Japan.