Plasminogen activator inhibitor-1 is associated with renal dysfunction independent of BMI and serum lipid levels in patients with type 2 diabetes
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- 作者：Jun Shirakawa ; Yu Togashi ; Kazuki Tajima ; Kazuki Orime ; Kaori Kikuchi ; Takashi Miyazaki ; Koichiro Sato ; Mari Kimura ; Yoshio Goshima ; Yasuo Terauchi
- 关键词：PAI-1 ; eGFR ; Type 2 diabetes
- 刊名：Diabetes Research and Clinical Practice
- 出版年：2012
- 出版时间：July, 2012
- 年：2012
- 卷：97
- 期：1
- 页码：e9-e12
- 全文大小：202 K
文摘
We investigated a possible association between serum plasminogen activator inhibitor-1 (PAI-1) levels and renal dysfunction in 124 type 2 diabetes patients. Multiple linear regression analyses indicated that the PAI-1 levels were significantly inversely correlated with estimated glomerular filtration rate (eGFR) independent of albuminuria, BMI, LDL-C, and triglyceride.