Estimated intake levels for Finnish children of methylmercury from fish

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• 作者：Anna K. Karjalainen^a ; ^b ; ^{anna.karjalainen@ymparisto.fi} ; ^{anna.k.karjalainen@jyu.fi} ; Anja Hallikainen^c ; Tero Hirvonen^c ; Hannu Kiviranta^d ; Mikael Knip^e ; ^f ; Carina Kronberg-Kippilä ; ^g ; Olli Leino^d ; Olli Simell^h ; Harri Sinkko^g ; Jouni T. Tuomisto^d ; Riitta Veijolaⁱ ; Eija-Riitta Venä ; lä ; inen^c ; Suvi M. Virtanen^g ; ^j ; ^k
• 关键词：Children ; Concentration ; Finland ; Fish consumption ; Intake ; MeHg
• 刊名：Food and Chemical Toxicology
• 出版年：2013
• 出版时间：April, 2013
• 年：2013
• 卷：54
• 期：Complete
• 页码：70-77
• 全文大小：480 K

文摘

Methylmercury (MeHg) is a well-known neurotoxic agent, and consumption of contaminated fish is the principal environmental source of MeHg exposure in humans. Children are more susceptible to adverse effects than adults. No previous specific data exist for intake by Finnish children of methylmercury from fish. We estimated fish consumption and MeHg intakes from species most commonly consumed by Finnish children aged 1-6 years. The total mercury concentrations were determined in fish species consumed, and age-specific methylmercury intakes were derived. We also examined safety margins and the proportion of children exceeding the tolerable daily intakes set by international expert bodies. The daily intake of MeHg ranged from 0 to 0.33 ¦Ìg/kg bw. The strictest reference value 0.1 ¦Ìg/kg bw/day for MeHg, proposed by USEPA, was exceeded by 1-15 % of the study population, and FAO/WHO JECFA provisional tolerable weekly intake of 1.6 ¦Ìg/kg bw was exceeded by 1 % of boys and 2.5 % of girls aged 6 years. Intakes of 1-year old girls were higher than of boys, whereas for 3-year olds they were the opposite. The highest intakes were observed for 6-year-old boys and girls. There was great variation in the estimated MeHg intakes among Finnish children.