Individual methylmercury intake estimates from local seafood of the Mediterranean Sea, in Italy

详细信息    查看全文

• 作者：Elena Dellatte^a ; ^{elena.dellatte@iss.it" class="auth_mail} ; Gianfranco Brambilla^a ; ^{gianfranco.brambilla@iss.it" class="auth_mail} ; Roberto Miniero^a ; ^{roberto.miniero@iss.it" class="auth_mail} ; Maria Cesarina Abete^b ; ^{mariacesarina.abete@izsto.it" class="auth_mail} ; Roberta Orletti^c ; ^{r.orletti@izsum.it" class="auth_mail} ; Giannina Chessa^d ; ^{giannina.chessa@izs-sardegna.it" class="auth_mail} ; Alessandro Ubaldi^e ; ^{alessandro.ubaldi@izslt.it" class="auth_mail} ; Eugenio Chiaravalle^f ; ^{izsfgchimica@tiscali.it" class="auth_mail} ; Micaela Tiso^g ; ^{micaela.tiso@unige.it" class="auth_mail} ; Angelo Ferrari^g ; ^{angelo.ferrari@izsto.it" class="auth_mail}
• 关键词：bw ; body weight ; EC ; European Commission ; EFSA ; European Food Safety Authority ; EU ; European Union ; FAO ; Food and Agriculture Organization of the United Nations ; FFQ ; Food Frequency Questionnaire ; Hg ; mercury ; HgTOT ; total mercury ; IQ ; intelligence quotient ; JECFA ; Joint FAO/WHO Expert Committee on Food Additives ; LC-PUFA ; Long Chained Poly-Unsaturated Fatty Acid ; MAD ; Median Absolute Deviation ; MeHg ; methylmercury ; MRL ; Maximum Residue Limit ; RDA ; Recommended Daily Allowance ; RfD ; Reference Dos
• 刊名：Regulatory Toxicology and Pharmacology
• 出版年：June, 2014
• 年：2014
• 卷：69
• 期：1
• 页码：105-112
• 全文大小：1085 K

文摘

A Seafood Frequency Questionnaire (SFQ) broken down in more than 42 items with 8-week coverage was interview-administered to 278 adults aged 19-82 years (167 women, 98 in the reproductive age 19-45 years, and 111 men), resident on the Italian Mediterranean shore and frequent buyer at local fish markets. Methylmercury (MeHg) intake on individual basis was estimated for a selected occurrence equal to the median value + Median Absolute Deviation (MAD) in each seafood species reported (conservative scenario). MeHg occurrence was derived from an extensive seafood database referred to years 2009-2011. Accounting for an average body weight of 62.2 kg, 24.6% of women resulted overexposed with respect to the European Food Safety Authority (EFSA) Tolerable Weekly Intake (TWI) for MeHg of 1.3 渭g/kg bw, with a mean of 0.92 渭g/kg bw. In the vulnerable group aged 19-45 years, 29.6% exceeded the TWI. Rather than the amount of seafood consumed, the seafood choice appears to be the main determinant of the MeHg intake. Risk awareness was reported in the 49% of SFQs. Uncertainties related to such estimates from questionnaires are discussed, in order to give adequate health recommendations without compromising seafood consumption in the Mediterranean region.