A fatal complication of tirofiban in an octogenarian: Diffuse alveolar hemorrhage

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• 作者：Erkan ?lhan ; MD ; ^{erkan.ilhan@yahoo.com.tr} ; Tolga Sinan G&uuml ; venç ; MD ; Ö ; zge G&uuml ; zelburç ; MD ; Servet Altay ; MD ; Nihat Ö ; zer ; MD ; Ö ; zer Soylu ; MD ; Hakan Hasdemir ; MD ; Mehmet Ergelen ; MD
• 关键词：Glycoprotein IIb/IIIa antagonist ; Tirofiban ; Acute coronary syndrome ; Diffuse alveolar hemorrhage
• 刊名：Journal of Cardiology Cases
• 出版年：2010
• 出版时间：August 2010
• 年：2010
• 卷：2
• 期：1
• 页码：e48-e51
• 全文大小：494 K

文摘

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Summary

An 84-year-old female patient with a past medical history significant for hypertension and diabetes mellitus, was admitted to the Emergency Department with acute coronary syndrome and complete atrioventricular block. She underwent a successful primary percutaneous coronary intervention. Ten minutes following tirofiban administration, the patient complained of hemoptysis and severe dyspnea. After chest X-ray and diagnostic bronchoscopy, she was diagnosed with diffuse alveolar hemorrhage. She died because of respiratory insufficiency on the third day of hospitalization. We present the first tirofiban-related diffuse alveolar hemorrhage case caused with half of the recommended dose of tirofiban used in the setting of non-ST-elevation myocardial infarction.