The role of bacteriological studies in the management of peritonsillar abscess

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• 作者：Tomoyasu Tachibana^a ; Yorihisa Orita^b ; ^{y.orita@live.jp" class="auth_mail" title="E-mail the corresponding author} ; Soshi Takao^c ; Yuya Ogawara^a ; Yuko Matsuyama^a ; Aiko Shimizu^a ; Iku Abe-Fujisawa^b ; Michihiro Nakada^d ; Yasuharu Sato^e ; Kazunori Nishizaki^b
• 关键词：Peritonsillar abscess ; Culture test ; Microbiology ; Laryngeal edema ; Smoker
• 刊名：Auris Nasus Larynx
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：43
• 期：6
• 页码：648-653
• 全文大小：447 K

文摘

Since most patients with peritonsillar abscess (PTA) can be successfully treated with surgical drainage and empirical antibiotic therapy, routine bacteriologic studies for all patients with PTA may be unnecessary. This study tried to evaluate which patients with PTA should certainly undergo bacteriologic studies.

Methods

Hundred consecutive patients with PTA were treated and underwent culture tests of purulent contents obtained by surgical drainage between April 2008 and December 2013.

Results

In 62 of the 100 patients, 71 pathogenic bacteria were identified; 61 (86%) were Gram-positive cocci (GPC), 8 (11%) were Gram-negative rods (GNR), and 6 (8%) were anaerobes. Normal flora were isolated in 27 patients, and culture results were negative in 11 patients. Although not significant, primary (without prior antibiotic therapy) case (odds ratio (OR) = 2.19; 95% CI, 0.95–5.05) and laryngeal edema (OR = 2.04; 95% CI, 0.82–5.03) showed a tendency of associations with detection of pathogenic bacteria. After taking into account interactions between smoking habit and laryngeal edema, the covariate-adjusted OR for non-smokers with laryngeal edema was significant and showed a strong relationship (OR = 7.43; 95% confidence interval, 1.05–52.73) compared to non-smokers without laryngeal edema.

Conclusion

Although empirical antibiotic therapy was effective for most of the PTA patients, bacteriologic studies might be indispensable for the patients with laryngeal edema considering the failure of the first treatments. Particularly, the culture tests may be useful for non-smokers with laryngeal edema.