Atypical serum transferrin isoform distribution in liver cirrhosis studied by HPLC, capillary electrophoresis and transferrin genotyping
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- 作者：Torsten Arndt ; Brenda B. van der Meijden ; Jos P.M. Wielders
- 关键词：Capillary electrophoresis ; CDT ; HPLC ; Liver cirrhosis ; Transferrin isoforms
- 刊名：Clinica Chimica Acta
- 出版年：2008
- 出版时间：August 2008
- 年：2008
- 卷：394
- 期：1-2
- 页码：42-46
- 全文大小：452 K
文摘
An incomplete separation of disialotransferrin (CDT) and trisialotransferrin (a non-CDT isoform) may cause false-positive CDT results in alcohol abuse testing. We describe a currently unknown disialotransferrin-trisialotransferrin-bridging phenomenon (di-tri-bridge) appearing with high prevalence in serum from liver cirrhosis patients.