Targetting αvβ3 and α5β1 integrins with Ecballium elaterium (L.) A. Rich. seed oil
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- 作者：Imen Touihri-Barakati<sup>asup><sup> ; sup><sup>imen.touihri@gmail.comsup> ; Olfa Kallech-Ziri<sup>asup> ; Abdennacer Boulila<sup>asup> ; Khaoula Khwaldia<sup>asup> ; Naziha Marrakchi<sup>bsup><sup> ; sup><sup>csup> ; Belgacem Hanchi<sup>dsup> ; Karim Hosni<sup>asup> ; José ; Luis<sup>esup>
- 关键词：Ecballium elaterium ; Seed oil ; αvβ3 and α5β1 integrins ; Adhesion ; Angiogenesis ; Glioma cell line
- 刊名：Biomedicine & Pharmacotherapy
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：84
- 期：Complete
- 页码：1223-1232
- 全文大小：2361 K
- 卷排序：84
文摘
Ecballium elaterium seed oil inhibits cell adhesion of human glioma cell line U87. E. elaterium seed oil abolishes migration of human glioma cell line. Seed oil displays anti-angiogenic activity on HMEC-1 cells. The anti-tumor effect is mediated specifically by αvβ3 and α5β1 integrins.