Large-pore mesoporous silica nanospheres as vehicles for delivering TRAF3-shRNA plasmids to Kupffer cells
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- 作者：Junyong Zhanga ; zhangmachine@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Shipeng Guob ; guoshipeng2008@126.com" class="auth_mail" title="E-mail the corresponding author ; Wenfeng Zhangb ; Sadengren8881@163.com" class="auth_mail" title="E-mail the corresponding author ; Dechao Niuc ; niudechao_2002@163.com" class="auth_mail" title="E-mail the corresponding author ; Jianping Gongb ; gjp_cqmu@yeah.net" class="auth_mail" title="E-mail the corresponding author
- 关键词：Engineered nanomaterials ; DNA transfection ; Inherent macrophages of liver ; TRAF3
- 刊名：Biochemical and Biophysical Research Communications
- 出版年：2016
- 出版时间：8 January 2016
- 年：2016
- 卷：469
- 期：2
- 页码：196-202
- 全文大小：2420 K
文摘
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We constructed Large-Pore Mesoporous Silica Nanospheres (LPMSNs).
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LPMSNs adsorbed high quantity of plasmid.
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Low cytotoxicity of LPMSNs to Kupffer cells.
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LPMSNs delivered plasmid into Kupffer cells.