Retinoic acid-inducible gene-I-like receptor (RLR)-mediated antiviral innate immune responses in the lower respiratory tract: Roles of TRAF3 and TRAF5
详细信息 查看全文
- 作者：Yuki Chibaa ; Tomoh Matsumiyab ; tomo1027@hirosaki-u.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Tsugumi Satohc ; Ryo Hayakarib ; Ken Furudated ; Fei Xingb ; Hidemi Yoshidab ; Kunikazu Tanjie ; Hiroki Mizukamic ; Tadaatsu Imaizumib ; Etsuro Itoa
- 关键词：RLRs ; Lower respiratory tract ; Antiviral signaling ; TRAF3 ; TRAF5
- 刊名：Biochemical and Biophysical Research Communications
- 出版年：2015
- 出版时间：13 November 2015
- 年：2015
- 卷：467
- 期：2
- 页码：191-196
- 全文大小：983 K
文摘
- •
Epithelial cells in the LTR can express type I IFN in response to double-stranded RNA.
- •
TRAF3 and TRAF5 are involved in RLR signaling in the LRT.
- •
BECs express the highest levels of TRAF3 and TRAF5 in the LTR.