Long-Term Survival of Primary Intracranial Plasmablastic Lymphoma: Case Report and Review of the Literature

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• 作者：Hui Ma¹ ; Ming-Hai Wei² ; Hua-Min Qin³ ; Guan-Yu Wang² ; Zeng-Chun Hu² ; ^{huzengchun@hotmail.com}
• 关键词：Intracranial ; Plasmablastic lymphoma ; Prognosis ; Therapy
• 刊名：World Neurosurgery
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：97
• 期：Complete
• 页码：750.e5-750.e10
• 全文大小：3797 K
• 卷排序：97

文摘

Primary intracranial plasmablastic lymphoma (PIPBL) is a rare malignant tumor.Case DescriptionWe present a case of PIPBL in a 32-year-old man who complained of a progressive growing, painful mass on the right parieto-occipital part of head. Computed tomography and magnetic resonance imaging revealed a homogeneously enhanced mass with partial bone destruction. The patient underwent total resection and cranioplasty in one stage. Histopathologic examination showed large tumor cells with immunoblast-like nuclei. Immunohistochemical staining displayed CD38(+), CD138(+), Mum-1(+), CD20(−), and PAX-5(−). The patient received chemotherapy. The patient has survived more than 3.5 years after operation, with follow-up. We also review the clinical data, molecular pathologic traits, treatment, and prognosis of additional 6 cases with PIPBL in the literature.ConclusionsThis study provides important clinical information for the diagnosis and treatment of PIPBL.