Polymorphisms in human telomerase reverse transcriptase (hTERT) gene and susceptibility to gastric cancer in a Turkish population: Hospital-based case-control study
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- 作者：Sü ; leyman Bayrama ; slymnbyrm81@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Yakup Ü ; lgerb ; Ahmet Taner Sü ; mbü ; lc ; Berrin Yalinbaş Kayad ; Ahmet Genç ; e ; Eyyü ; p Rencü ; zoğullarif ; Erdoğan Dadaşg
- 关键词：ALL ; acute lymphoblastic leukemia ; BC ; breast cancer ; CI ; confidence interval ; GC ; gastric cancer ; gDNA ; genomic DNA ; ht ; haplotype ; hTERT ; human telomerase reverse transcriptase ; HWE ; Hardy&ndash ; Weinberg equilibrium ; LC ; lung cancer ; MAF ; minimum allele frequency ; OR ; odds ratios ; PC ; prostate cancer ; PCR&ndash ; RFLP ; polymerase chain reaction&ndash ; restriction fragment length polymorphism ; SCCHN ; squamous cell carcinoma of the head and neck ; SNP ; single nucleotide polymorphism
- 刊名：Gene
- 出版年：2016
- 出版时间：1 July 2016
- 年：2016
- 卷：585
- 期：1
- 页码：84-92
- 全文大小：360 K
文摘
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hTERT rs2736109 G > A, rs2735940 T > C, and rs2736100 T > G were associated with risk of GC.
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Grs2736109/Trs2735940/Ars2853669/Grs2736100 haplotype was increased risk of GC.
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Further studies with larger sample size and in different populations are warranted.