Oxirane synthesis from diazocarbonyl compounds via NHC-Ag⁺ catalysis

详细信息    查看全文

• 作者：Zhen Wang ; Jian Wen ; Qing-Wei Bi ; Xiao-Qi Xu ; Zhu-Qing Shen ; Xiao-Xiao Li ; Zili Chen ; ^{zilichen@ruc.edu.cn" class="auth_mail}
• 关键词：N-Heterocyclic carbene silver complex ; Carbene transfer reaction ; Silver carbenoid ; Oxirane synthesis
• 刊名：Tetrahedron Letters
• 出版年：30 April 2014
• 年：2014
• 卷：55
• 期：18
• 页码：2969-2972
• 全文大小：685 K

文摘

A new method was developed to synthesize oxirane products from the reaction of diazocarbonyl substrates with aryl aldehydes by using Ag(I) N-heterocyclic carbene complex as the catalyst. A combination of N-heterocyclic carbene silver complex (IPrAgCl) with another silver salt (AgOTf) generated the catalytic active IPr-Ag⁺ intermediate, which then catalyzed the epoxidation reaction.