Genetic manipulation of the bifunctional gene, carRA, to enhance lycopene content in Blakeslea trispora
文摘
Manipulation of carRA in B. trispora was conducted using gene targeting technology. Disruption of carR enhanced the lycopene but decreased total carotenoid content. Overexpression of carA increased the lycopene and the total carotenoid content. The target of tripropylamine is the R domain, rather than the A domain, of CarRA.