Exploring optimal control strategies in seasonally varying flu-like epidemics

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• 作者：Sunmi Lee^a ; ^{sunmilee@khu.ac.kr} ; Gerardo Chowell^b ; ^c
• 关键词：Influenza transmission dynamics ; Seasonally varying transmission rate ; Optimal control theory ; Vaccination and treatment strategies
• 刊名：Journal of Theoretical Biology
• 出版年：2017
• 出版时间：7 January 2017
• 年：2017
• 卷：412
• 期：Complete
• 页码：36-47
• 全文大小：1290 K
• 卷排序：412

文摘

Epidemic dynamics with seasonal transmission rates are analyzed. Optimal control interventions are investigated under seasonal transmission rates. Epidemic outcomes are found to be highly sensitive to changes in various parameters. Epidemic forecasting with seasonal transmission rates faces many challenges.