Dual-color imaging technique was used to observe the axonal transport dynamics between axonal cargos and stationary organelles in dorsal root ganglion neurons.
Axonal cargos tend to transiently slow down, or pause within the vicinity of the stationary organelles, suggesting that stationary organelles can pose as mild steric hindrance to axonal transport.
Further investigations are needed to understand the causative or correlative relationship between stationary organelles and transport delays of axonal cargoes.