Glutamate, central cholinergic, GABAergic deficiency plays a critical role in AD.
10">vGluT1, vGluT3 and vAChT is more sensitive than vGluT2, vGAT in VD.
15">At the same time, CA1, CA2, CA3 circuits play an important role in the social, emotional, and temporal n spatial aspects of memory.
So, vGlut1, vGlut3 and vAChT may be the important synaptic nerve terminals in CCI-induced VD.