A modified beam-walking apparatus for assessment of anxiety in a rodent model of blast traumatic brain injury
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- 作者：Brian M. Sweisa ; b ; c ; Salam P. Bachoura ; Julia A. Brekkea ; d ; Jonathan C. Gewirtze ; Homayoun Sadeghi-Bazarganif ; g ; Mario Hevesia ; b ; Afshin A. Divania ; d ; h ; divani@umn.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Anxiety ; Motor ; Elevated plus maze ; Modified beam-walking ; Blast traumatic brain injury ; Rats
- 刊名：Behavioural Brain Research
- 出版年：2016
- 出版时间：1 January 2016
- 年：2016
- 卷：296
- 期：Complete
- 页码：149-156
- 全文大小：1085 K
文摘
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Anxiety and motor function often suffers as a result of traumatic brain injury.
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Elevated plus maze and beam-walking tasks are used to test these traits in rodents.
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A novel task, the modified beam-walking apparatus, combines these tasks into one.
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Anxiety scores show agreement between this novel and standard tests post-injury.
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This novel task is capable of dissociating how injury affects motor versus anxiety.