A TRIM16-Galectin3 Complex Mediates Autophagy of Damaged Endomembranes

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• 作者：Milana Fraiberg¹ ; Zvulun Elazar¹ ; ^{zvulun.elazar@weizmann.ac.il" class="auth_mail" title="E-mail the corresponding author}
• 刊名：Developmental Cell
• 出版年：2016
• 出版时间：10 October 2016
• 年：2016
• 卷：39
• 期：1
• 页码：1-2
• 全文大小：899 K

文摘

Selective autophagy, an essential process for maintaining intracellular homeostasis, depends on precise target recognition and local activation. Reporting in Developmental Cell, Chauhan et al. (2016) elegantly demonstrate that interaction between TRIM16 and Galectin3 orchestrates the recruitment of core autophagic factors and activates selective autophagy at the site of damaged endomembranes.