TRIMs and Galectins Globally Cooperate and TRIM16 and Galectin-3 Co-direct Autophagy in Endomembrane Damage Homeostasis
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- 作者：Santosh Chauhan1 ; 4 ; 5 ; Suresh Kumar1 ; 4 ; Ashish Jain2 ; 4 ; 6 ; Marisa Ponpuak1 ; 3 ; 4 ; Michal H. Mudd1 ; Tomonori Kimura1 ; Seong Won Choi1 ; Ryan Peters1 ; Michael Mandell1 ; Jack-Ansgar Bruun2 ; Terje Johansen2 ; terje.johansen@uit.no" class="auth_mail" title="E-mail the corresponding author ; Vojo Deretic1 ; 7 ; vderetic@salud.unm.edu" class="auth_mail" title="E-mail the corresponding author
- 刊名：Developmental Cell
- 出版年：2016
- 出版时间：10 October 2016
- 年：2016
- 卷：39
- 期：1
- 页码：13-27
- 全文大小：5989 K
文摘
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TRIM proteins and Galectins interact
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TRIM16 works with Galectin-3 in recognition of damaged lysosomes and phagosomes
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TRIM16 controls autophagy to contain lysosomal damage and M. tuberculosis invasion
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TRIM16 affects mTOR and TFEB and controls lysosomal quality and quantity