Long noncoding RNAs: Lessons from genomic imprinting
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- 作者：Chandrasekhar Kanduri Kanduri.chandrasekhar@gu.se" class="auth_mail" title="E-mail the corresponding author
- 关键词：lncRNA ; long noncoding RNA ; DMR ; Differentially methylated region ; ICR ; Imprinting control region ; PWS ; Prader&ndash ; Willi syndrome ; AS ; Angelmann syndrome ; MEGs ; Maternally expressed genes ; TTS ; Triplex target sites ; TFO ; Triplex forming oligo ; IG-DMR ; Intergenic DMR ; RNAPII ; RNA polymerase II ; IGN ; Imprinted gene network ; MBD1 ; Methyl-binding domain 1 protein ; KSRP ; K homology-type splicing regulatory protein ; BWS ; Beckwith&ndash ; Wiedemann sydrome ; H3K27ac ; Histone H3 lysine 27 acetylation ; H3
- 刊名：Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：1859
- 期：1
- 页码：102-111
- 全文大小：837 K
文摘
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lncRNA regulate imprinted gene expression by transcription occlusion and collision.
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lncRNA establish crosstalk between two imprinted clusters to regulate gene expression.
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Enhancer RNA regulate genomic imprinting.
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lncRNA represses genes by establishing higher-order intra-chromosomal interactions.