IFNa of triploid hybrid of gold fish and allotetraploid is an antiviral cytokine against SVCV and GCRV
详细信息 查看全文
- 作者：Jun Yana ; 1 ; Lingzhi Penga ; 1 ; Yang Lia ; Hui Fana ; Yu Tiana ; b ; Shaojun Liua ; Hao Fenga ; fenghao@hunnu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Triploid hybrid ; IFN ; SVCV ; GCRV
- 刊名：Fish & Shellfish Immunology
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：54
- 期：Complete
- 页码：529-536
- 全文大小：1904 K
文摘
- •
One of the type I IFNs of triploid hybrid of gold fish and allotetroploid (3nIFNa) was cloned and characterized, which possesses much stronger disease-resistance ability than its parents.
- •
The mRNA transcription levels of 3nIFNa were obviously increased in all selected tissues after SVCV or GCRV infection.
- •
EPC cells treated with 3nIFNa-containing conditioned media or transfected with plasmid expressing 3nIFNa before SVCV or GCRV infection showed much enhanced antiviral ability.