Cameo appearances of aminoacyl-tRNA in natural product biosynthesis

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• 作者：Emily C Ulrich¹ ; ² ; Wilfred A van der Donk¹ ; ² ; ^{vddonk@illinois.edu}
• 刊名：Current Opinion in Chemical Biology
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：35
• 期：Complete
• 页码：29-36
• 全文大小：1610 K
• 卷排序：35

文摘

Aminoacyl-tRNA (aa-tRNA) is involved in the production of diverse natural products. Cyclodipeptide synthases interact with two aa-tRNAs at separate binding sites. Many natural product gene clusters encode FemX/MprF homologs that require aa-tRNA. Different RiPP classes require aa-tRNA for Ser/Thr dehydration.