First genome sequences of buffalo coronavirus from water buffaloes in Bangladesh

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• 作者：S.K.P. Lau¹ ; ² ; ³ ; ⁴ ; ^&dagger ; ; ^{skplau@hku.hk" class="auth_mail" title="E-mail the corresponding author} ; A.K.L. Tsang¹ ; ^&dagger ; ; S. Shakeel Ahmed¹ ; M. Mahbub Alam⁵ ; Z. Ahmed⁶ ; P.-C. Wong¹ ; K.-Y. Yuen¹ ; ² ; ³ ; ⁴ ; P.C.Y. Woo¹ ; ² ; ³ ; ⁴ ; ^{pcywoo@hku.hk" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Coronavirus ; water buffalo
• 刊名：New Microbes and New Infections
• 出版年：2016
• 出版时间：May 2016
• 年：2016
• 卷：11
• 期：Complete
• 页码：54-56
• 全文大小：380 K

文摘

We report the complete genome sequences of a buffalo coronavirus (BufCoV HKU26) detected from the faecal samples of two domestic water buffaloes (Bubalus bubalis) in Bangladesh. They possessed 98–99% nucleotide identities to bovine coronavirus (BCoV) genomes, supporting BufCoV HKU26 as a member of Betacoronavirus 1. Nevertheless, BufCoV HKU26 possessed distinct accessory proteins between spike and envelope compared to BCoV. Sugar-binding residues in the N-terminal domain of S protein in BCoV are conserved in BufCoV HKU26.