In vitro antioxidant, immunomodulatory and anticancer activities of two fractions of aqueous extract from Helicteres angustifolia L. root
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- 作者：Kejuan Li ; Xi Yang ; Xuansheng Hu ; Chao Han ; Zhongfang Lei ; Zhenya Zhang ; zhang.zhenya.fu@u.tsukuba.ac.jp" class="auth_mail" title="E-mail the corresponding author
- 关键词：Immunomodulatory ; Macrophages ; Cytotoxic ; Anticancer ; Antioxidant
- 刊名：Journal of the Taiwan Institute of Chemical Engineers
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：61
- 期：Complete
- 页码：75-82
- 全文大小：2973 K
文摘
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This is the first report on strong immunomodulatory effect of H. angustifolia L.
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EF and WF contained high contents of phenolics and polysaccharides, respectively.
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EF mainly contributed to the cytotoxicity of aqueous extract of this plant.
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WF showed remarkable immunomodulatory activity on macrophages RAW264.7 cells and was able to protect macrophages cells from doxorubicin induced toxicity and apoptosis.