Polysaccharides from the brown seaweed Padina tetrastromatica
详细信息 查看全文
- 作者：Paramita Karmakar ; Tuhin Ghosh ; Sharmistha Sinha ; Sudipta Saha ; Pinaki M ; al ; Pradyot K. Ghosal ; Bimalendu Ray
- 关键词：Padina tetrastromatica ; Dictyotaceae ; Structural features ; Sulfated fucan
- 刊名：Carbohydrate Polymers
- 出版年：2009
- 出版时间：15 October 2009
- 年：2009
- 卷：78
- 期：3
- 页码：416-421
- 全文大小：397 K
文摘
Sulfated fucans, the complex polysaccharides from brown seaweeds, possess various biological activities. To understand the structure activity relationship of sulfated fucans, we have investigated the structural features of one such polymer from Padina tetrastromatica using standard methods of carbohydrate structural analysis. We report a novel structural motif for this polymer. The average structure of this macromolecule that has a molecular mass of 25 kDa differs from the previous models in three respects. First, the core region of this macromolecule is composed primarily of α-(1 → 2)- and α-(1 → 3)-linked fucopyranosyl residues. Sulfate groups, when present are located at position 4 and 2 of fucosyl residues. Secondly, fucose and xylose is attached to this polymer to form branch points, one for every two residues within the chain. Finally, this macromolecule contained smaller amount of sulfate (0.21 mol of sulfate per mol of deoxyhexose).