Prognostic Value of Serial Measurements of Soluble Suppression of Tumorigenicity 2 and Galectin-3 in Ambulatory Patients With Chronic Heart Failure
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- 作者：Wayne L. Miller ; MD ; PhD1 ; miller.wayne@mayo.edu" class="auth_mail" title="E-mail the corresponding author ; Amy K. Saenger ; PhD2 ; Diane E. Grill ; MSc3 ; Joshua P. Slusser ; BS3 ; Antoni Bayes-Genis ; MD ; PhD4 ; Allan S. Jaffe ; MD1 ; 2
- 关键词：Serial biomarkers ; sST2 ; galectin-3 ; chronic heart failure
- 刊名：Journal of Cardiac Failure
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：22
- 期：4
- 页码：249-255
- 全文大小：283 K
文摘
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sST2 and galectin-3 target pathways leading to myocardial fibrosis.
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In time-dependent multivariate analysis, sST2 is an independent predictor.
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20">sST2 demonstrated incremental value in reclassifying patients to higher risk.
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25">Serial monitoring of sST2 but not galectin-3 identifies highest-risk HF outpatients.