FGF2 induces sST2 translation.
sST2-5′UTR contains an FGF2-responsive IRES element.
23 nucleotides within the sST2-5′UTR are required for optimal IRES activity.
20">Intact MEK/ERK signaling is required for FGF2-induced sST2-IRES activity.
25">hnRNP A1 binds to and activates the sST2-IRES.