2.P.371 In vivo thromboxane/prostacyclin balance unfavourable affected in humans after diets rich in stearic acid or trans fatty acids

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• 作者：Mutanen ; Marja ; Turpeinen ; Anu M. ; Wü ; bert ; Joachim ; Lorenz ; Reinhard ; Aro ; Antti
• 刊名：Atherosclerosis
• 出版年：1997
• 出版时间：October, 1997
• 年：1997
• 卷：134
• 期：1-2
• 页码：194
• 全文大小：155 K

文摘

The thrombogenic effects of stearic acid (C18:0) and trans fatty acids (transFA) are poorly known in humans. In this highly controlled dietary study, platelet activation was studied in healthy humans after diets rich in C18:0 or transFA. For 5 weeks 80 subjects consumed a baseline diet high in saturated FAs and were then switched to a diet containing 9.3 percent of energy (en % ) stearic acid or a diet containing 8.7 en % trans FAss from hydrogenated vegetable oils for 5 weeks. All diets contained 32.2-33.9 en % fat, 14.6-15.8 en % saturated plus trans FAs, 12.2-12.5 en % cis monounsaturated and 2.9-3.5 en % polyunsaturated FAs.