Simultaneous Diaphragm and Liver Resection: A Propensity-Matched Analysis of Postoperative Morbidity

详细信息    查看全文

• 作者：George Z. Li ; BS^a ; ^{george.li@dm.duke.edu} ; Jason L. Sloane ; MS^a ; Michael E. Lidsky ; MD^b ; Georgia M. Beasley ; MD^b ; Srinevas K. Reddy ; MD^c ; John E. Scarborough ; MD ; FACS^b ; Douglas S. Tyler ; MD ; FACS^b ; Ryan S. Turley ; MD^b ; Bryan M. Clary ; MD ; FACS^b
• 关键词：DR ; diaphragm resection ; LR ; liver resection ; NSQIP ; National Surgical Quality Improvement Program ; RVU ; relative value unit ; SSI ; surgical site infection
• 刊名：Journal of the American College of Surgeons
• 出版年：2013
• 出版时间：March, 2013
• 年：2013
• 卷：216
• 期：3
• 页码：402-411
• 全文大小：103 K

文摘

| Figures/TablesFigures/Tables | ReferencesReferences

Background

Although a concomitant diaphragm resection might be required at the time of hepatectomy to achieve tumor-free surgical margins, studies addressing its effect on postoperative morbidity and mortality have been inconclusive. The objective of this study was to determine whether the need for diaphragm resection at the time of hepatectomy truly increases 30-day morbidity or mortality using data from the American College of Surgeons National Surgical Quality Improvement Program.

Study Design

Data were obtained from the 2005-2010 American College of Surgeons National Surgical Quality Improvement Program Participant User Files based on CPT coding. All patients undergoing a simultaneous liver and diaphragm resection were propensity-matched to a subset of liver resection patients not undergoing a diaphragm resection. The main outcomes measures were 30-day mortality and morbidity.

Results

One hundred and ninety-two patients who underwent combined liver and diaphragm resection were matched to 192 patients treated with liver resection alone. The need for concomitant diaphragm resection was associated with a higher overall complication rate (38.54 % vs 28.65 % ; p?= 0.048), major complication rate (33.33 % vs 23.44 % ; p?= 0.030), and respiratory complication rate (14.06 % vs 7.81 % ; p?= 0.058). Postoperative mortality was similar between groups. Combined diaphragm and liver resection was also associated with longer operative times (median 311 minutes vs 247.5 minutes; p < 0.001), higher rates of intraoperative packed RBC transfusion (33.33 % vs 23.44 % ; p?= 0.037), and a longer length of hospitalization (median 7 vs 6 days; p?= 0.002).

Conclusions

The results of this study, when taken into account with those reported previously, suggest that the need for diaphragm resection at time of hepatectomy increases postoperative morbidity but not mortality.