Interaction of plant essential oil terpenoids with the southern cattle tick tyramine receptor: A potential biopesticide target

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• 作者：Aaron D. Grossp>ap>p> ; p>p>bp>p> ; p>p>1p> ; Kevin B. Temeyerp>cp> ; Tim A. Dayp>bp> ; Adalberto A. Pé ; rez de Leó ; np>cp> ; Michael J. Kimberp>bp>p> ; p>p>2p> ; Joel R. Coatsp>ap>p> ; p>p>2p>p> ; p>p>jcoats@iastate.edup>
• 关键词：Rhipicephalus microplus ; Southern cattle tick ; Monoterpenoid ; Essential oils ; Tyramine receptor ; Tyramine
• 刊名：Chemico-Biological Interactions
• 出版年：2017
• 出版时间：1 February 2017
• 年：2017
• 卷：263
• 期：Complete
• 页码：1-6
• 全文大小：739 K
• 卷排序：263

文摘

The calcium pathway is activated by using a Gαqi(5) G-protein chimera co-expressed with the tyramine receptor. The bicyclic monoterpenoid pulegone at 10 μM has an agonistic effect on the tyramine receptor. Several monoterpenoids and related aromatic compounds enhance the response of tyramine at the tyramine receptor.