Low-dose steroid therapy in PARDS is feasible and may improve ventilation and oxygenation.
The molecular mechanisms underlying potential changes in these outcomes remained unclear.
This study examines the effects of IV methylprednisolone on plasma biomarkers of PARDS.
We simultaneously measured cytokines, cell counts and coagulation parameters in PARDS.
We report statistical models useful for future RCTs to predict ARDS severity and outcomes.