New synthetic approaches to 2-perfluoroalkyl-4H-pyran-4-ones

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• 作者：Tyvorskii ; Vladimir I. ; Bobrov ; Denis N. ; Kulinkovich ; Oleg G. ; De Kimpe ; Norbert ; Tehrani ; Kourosch Abbaspour
• 刊名：Tetrahedron
• 出版年：1998
• 出版时间：March 19, 1998
• 年：1998
• 卷：54
• 期：12
• 页码：2819-2826
• 全文大小：389 K

文摘

A convenient synthesis of 5-substituted 2-perfluoroalkyl-4H-pyran-4-ones by dehydration of 2,3-dihydro-3-hydroxy-6-perfluoroalkyl-4H-pyran-4-ones is described. The 6-substituted and parent 2-perfluoroalkyl-4H-pyran-4-ones have been more successfully prepared using the condensation of alkyl enol ethers, derived from β-dicarbonyl compounds, with ethyl perfluoroalkanoates.