A Single-Center Pilot Prospective Study of Topical Application of Platelet-Derived Eye Drops for Patients with Ocular Chronic Graft-versus-Host Disease
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- 作者：Francesco Zallio1 ; fazallio@ospedale.al.it" class="auth_mail" title="E-mail the corresponding author ; Laura Mazzucco2 ; Federico Monaco1 ; Maria Rosa Astori3 ; Roberto Passera4 ; Giovanna Drago1 ; Stefania Tamiazzo1 ; Manuela Rapetti5 ; Daniela Dolcino3 ; Roberto Guaschino2 ; Massimo Pini1 ; Marco Ladetto1
- 关键词：Lysed platelet concentrate ; Eye drops ; Allogeneic transplantation ; Graft-versus-host disease
- 刊名：Biology of Blood and Marrow Transplantation
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：22
- 期：9
- 页码：1664-1670
- 全文大小：842 K
文摘
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There currently are unsatisfactory results and no consensus about treatment in ocular chronic graft-versus-host disease
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We performed a single-center prospective pilot study regarding topical application of an autologous platelet concentrate, which was lysed and then reconstituted as eyes drops
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Survival rates of patients with ocular chronic graft-versus-host disease are similar to those with limited chronic graft-versus-host disease