Feasibility study of the natural derived chitosan dialdehyde for chemical modification of collagen
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- 作者：Xinhua Liua ; b ; Nianhua Dana ; b ; Weihua Dana ; b ; danweihua_scu@126.com" class="auth_mail" title="E-mail the corresponding author ; Juxia Gonga ; b
- 关键词：Collagen ; Chitosan dialdehyde ; Modification
- 刊名：International Journal of Biological Macromolecules
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：82
- 期：Complete
- 页码：989-997
- 全文大小：3263 K
文摘
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The biocompatible OCS is prepared successfully for the modification of collagen.
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The more stable Schiff's base is formed between collagen and OCS.
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The OCS inherits chitosan's superior antibacterial activity.
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Introducing OCS into collagen may be favorable for the cell's adhesion, growth and proliferation.
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The effect of OCS on the fibrillogenesis of collagen was also analyzed in detail.