刊名:Biochimica et Biophysica Acta (BBA) - General Subjects
出版年:2017
出版时间:January 2017
年:2017
卷:1861
期:1
页码:3095-3105
全文大小:1833 K
卷排序:1861
文摘
Crystal structures of apo-SIAH2 and USP19/SIAH1 complex are solved. USP19 is the only deubiquitinase found to bind with SIAH E3 ubiquitin ligases. The USP19/SIAH complex is conserved in evolution. Menadione destabilizes both SIAH1 and SIAH2 non-specifically.