Aquaporin-2 Ser-261 phosphorylation is regulated in combination with Ser-256 and Ser-269 phosphorylation

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• 作者：Naofumi Yui ; ^{nyui.kid@tmd.ac.jp} ; Sei Sasaki ; Shinichi Uchida
• 关键词：Aquaporin-2 ; Phosphorylation ; Dephosphorylation ; Vasopressin ; Forskolin ; MDCK
• 刊名：Biochemical and Biophysical Research Communications
• 出版年：2017
• 出版时间：22 January 2017
• 年：2017
• 卷：482
• 期：4
• 页码：524-529
• 全文大小：514 K
• 卷排序：482

文摘

A phospho-specific AQP2 isolation technique was developed. Ser-269 phosphorylation precedes Ser-261 dephosphorylation. Regulated Ser-269 phosphorylation occurs in pS256-positive AQP2. Regulated Ser-261 dephosphorylation occurs in pS256-positive AQP2. Regulated Ser-261 dephosphorylation occurs in pS269-positive AQP2.