Rapid screening and quantitative determination of bioactive compounds from fruit extracts of Myristica species and their in vitro antiproliferative activity
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- 作者：Renu Pandeya ; b ; Rohit Mahara ; b ; Mohammad Hasanainc ; Sanjeev K. Shuklaa ; b ; Jayanta Sarkarc ; K.B. Rameshkumard ; Brijesh Kumara ; b ; brijesh_kumar@cdri.res.in" class="auth_mail" title="E-mail the corresponding author ; gbrikum@yahoo.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Myristica species ; LC&ndash ; MS/MS ; NMR ; In vitro antiproliferative activity
- 刊名：Food Chemistry
- 出版年：2016
- 出版时间：15 November 2016
- 年：2016
- 卷：211
- 期：Complete
- 页码：483-493
- 全文大小：1724 K
文摘
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Twenty-one compounds were identified from four Myristica species by HPLC-QTOF-MS/MS.
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Seventeen compounds were reported first time from M. beddomeii and sixteen from M. fatua.
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Quantification of five major bioactive compounds was carried out by UHPLC-QqQLIT-MS/MS.
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Highest total content of five major active compounds was found in mace of M. fragrans.
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Evaluation of in vitro anti-proliferative activity revealed potent activity in Myristica species.