Host-pathogen interactions in malaria: cross-kingdom signaling and mitochondrial regulation
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- 作者：Shirley Luckhart1 ; sluckhart@ucdavis.edu" class="auth_mail" title="E-mail the corresponding author ; Nazzy Pakpour1 ; Cecilia Giulivi2
- 刊名：Current Opinion in Immunology
- 出版年：2015
- 出版时间：October 2015
- 年：2015
- 卷：36
- 期：Complete
- 页码：73-79
- 全文大小：601 K
文摘
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Mosquitoes and humans share many responses to malaria parasite infection.
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Conserved signaling regulates barrier and mitochondrial function during infection.
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Parasite success in both insect and human hosts likely depends on this conservation.
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This biology can be translated to novel drugs with transmission blocking activity.