Seroprevalence of Toxoplasma gondii among pregnant women in Almadinah Almunawwarah KSA

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• 作者：Naglaa F.A. Imam ; MD^a ; ^{naglaa-fouad@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; Esra'a A.A. Azzam ; M. Sc.^b ; Ahmed A. Attia ; MD^c
• 关键词：Almadinah Almunawwarah ; ELISA ; KSA ; Pregnancy ; Toxoplasma ; TOXO rapid test
• 刊名：Journal of Taibah University Medical Sciences
• 出版年：2016
• 出版时间：June 2016
• 年：2016
• 卷：11
• 期：3
• 页码：255-259
• 全文大小：1113 K

文摘

Given its detrimental obstetric and congential sequelae, the detection of primary toxoplasmosis is most critical during pregnancy. This study aims to detect the seroprevalence of Toxoplasma gondii (Toxoplasma gondii) among pregnant women who either have histories suggestive of toxoplasmosis or may be at risk.

Methods

Serum samples of 150 pregnant women aged 18–45 years were tested by the rapid Toxoplasma test (TOXO IgM/IgG test, InTec). The results were further confirmed by the enzyme-linked immunosorbent assay (ELISA) technique for IgM and IgG.

Results

Serological results of toxoplasmosis seropositivity were statistically analyzed in light of the available epidemiological data. Thirty-two cases (21.3%) were IgG positive, and none was IgM positive, as shown by both tests.

Conclusion

Significant relations were observed between seropositivity, maternal age and history of abortion, and probability of delivering a child with a congenital anomaly. Despite the lack of evidence of recent infection in this study, the high rates of T. gondii seropositivity among pregnant women signaled a threat of primary exposure during pregnancy.