The reasonable subject setting of safety engineering has an effect on the culturing of safety talents which is related to the safe operation of our enterprises. Through the use of fuzzy comprehensive evaluation method the mathematical model of the rationality evaluation of talent training mode is established. Taking Kunming University of Science and Technology for example, evaluation indexes of rationality of talent training mode are obtained through the use of fuzzy comprehensive evaluation. It is showed that the highly ambiguous talent training mode can be quantified in accordance with fuzzy comprehensive evaluation model. It provides us with foundation of scheme design of talent training mode.