Biotransformation of synthetic cannabinoids JWH-018, JWH-073 and AM2201 by Cunninghamella elegans
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- 作者：Shimpei Watanabea ; 1 ; Unnikrishnan Kuzhiumparambila ; b ; 1 ; Zofia Winiarskic ; Shanlin Fua ; shanlin.fu@uts.edu.au" class="auth_mail" title="E-mail the corresponding author
- 关键词：Synthetic cannabinoids ; Metabolism ; Cunninghamella elegans ; JWH-018 ; JWH-073 ; AM2201
- 刊名：Forensic Science International
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：261
- 期：Complete
- 页码：33-42
- 全文大小：1478 K
文摘
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The fungus Cunninghamella elegans can metabolize JWH-018, JWH-073 and AM2201.
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The majority of the metabolites was produced via phase I metabolism.
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The fungal metabolites were found to be in good agreement with the human metabolites.