Assessment of neuroactive steroids in cerebrospinal fluid comparing acute relapse and stable disease in relapsing-remitting multiple sclerosis
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- 作者：NS. Oreficea ; nicola.o@icloud.com" class="auth_mail" title="E-mail the corresponding author ; A. Carotenutod ; carotenuto.antonio87@gmail.com" class="auth_mail" title="E-mail the corresponding author ; G. Mangoneb ; gra.mangone@yahoo.it" class="auth_mail" title="E-mail the corresponding author ; B. Buesc ; bastianbues@gmail.com" class="auth_mail" title="E-mail the corresponding author ; R. Rehmc ; ronja_rehm@gmx.de" class="auth_mail" title="E-mail the corresponding author ; I. Cerillod ; ilaria.cerillo@libero.it" class="auth_mail" title="E-mail the corresponding author ; F. Saccà ; d ; francesco.sacca@unina.it" class="auth_mail" title="E-mail the corresponding author ; A. Calignanoa ; calignan@unina.it" class="auth_mail" title="E-mail the corresponding author ; G. Oreficed ; orefice@unina.it" class="auth_mail" title="E-mail the corresponding author
- 关键词：Pregnenolone ; Dehydroepiandrosterone ; Allopregnanolone ; Cerebrospinal fluid ; Multiple sclerosis ; Acute relapse ; Neuroprotection
- 刊名：Journal of Steroid Biochemistry and Molecular Biology
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：159
- 期：Complete
- 页码：1-7
- 全文大小：959 K
文摘
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Neuroactive steroids evaluation in male and female relapsing-remitting multiple sclerosis.
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Disease activity influences the neuroactive steroids metabolism in multiple sclerosis.
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More variations of neuroactive steroids metabolism in women than men multiple sclerosis.
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Increase of PREG and DHEA values in CSF of male and female relapsing-remitting multiple sclerosis.
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ALLO values significantly lower in female RR-MS patients.