fMRI study of olfaction in the olfactory bulb and high olfactory structures of rats: Insight into their roles in habituation
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- 作者：Fuqiang Zhao ; fuqiang_zhao@merck.com" class="auth_mail" title="E-mail the corresponding author ; Xiaohai Wang ; Hatim A. Zariwala ; Jason M. Uslaner ; Andrea K. Houghton ; Jeffrey L. Evelhoch ; Donald S. Williams ; Christopher T. Winkelmann
- 关键词：fMRI ; CBV ; Olfactory adaptation ; Olfactory bulb ; Piriform cortex ; Excitation rebound
- 刊名：NeuroImage
- 出版年：2016
- 出版时间：15 February 2016
- 年：2016
- 卷：127
- 期：Complete
- 页码：445-455
- 全文大小：1914 K
文摘
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CBV fMRI with USPIO was used to study odorant-induced olfaction in rats.
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Activations were observed in the olfactory bulb (OB) and higher olfactory regions (HOR).
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Responses to repeated stimulations adapted more in HOR than in OB.
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During continuous odor exposures, adaptation was only observed in HOR, not OB.
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The results support that HOR plays a more significant role than OB in habituation.