Eradication of Taenia solium cysticercosis: a role for vaccination of pigs

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• 作者：Lightowlers ; Marshall W.
• 刊名：International Journal for Parasitology
• 出版年：1999
• 出版时间：June 1, 1999
• 年：1999
• 卷：29
• 期：6
• 页码：811-817
• 全文大小：99.2 K

文摘

Neurocysticercosis due to Taenia solium is an important cause of human morbidity and mortality, particularly in Latin America and parts of Africa and Asia. The disease has been recognised as potentially eradicable. Emphasis has been placed on control of the parasite through mass chemotherapy of human populations to remove tapeworm carriers. This strategy does not control the source of tapeworm infections, cysticercosis in pigs, and parasite transmission may continue due to incomplete chemotherapy coverage of human tapeworm carriers or because of immigration of tapeworm carriers into control areas. Exceptionally effective, practical vaccines have been developed against cysticercosis in sheep and cattle and a recent trial has proved recombinant antigens to be effective against Taenia solium cysticercosis in pigs. A new strategy for eradication of Taenia solium is proposed, based principally on a combined approach of chemotherapy of human tapeworm carriers and vaccination of all pigs at risk of infection. Publisher: Elsevier Science Language of Publication: English Item Identifier: S0020-7519(99)00051-X Publication Type: Article ISSN: 0020-7519 Cited by:

1. Lightowlers, Marshall W.; Gauci, Charles G.,""Vaccines against cysticercosis and hydatidosis""Veterinary Parasitology2001pp. 337-352
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2. Huerta, M.; de Aluja, A.S.; Fragoso, G.; Toledo, A.; Villalobos, N.; Hernandez, M.; Gevorkian, G.; Acero, G.; Diaz, A.; Alvarez, I.; Avila, R.; Beltran, C.; Garcia, G.; Martinez, J.J.; Larralde, C.; Sciutto, E.,""Synthetic peptide vaccine against Taenia solium pig cysticercosis: successful vaccination in a controlled field trial in rural Mexico""Vaccine2001pp. 262-266
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3. Gauci, Charles G.; Lightowlers, Marshall W.,""Alternative splicing and sequence diversity of transcripts from the oncosphere stage of Taenia solium with homology to the 45W antigen of Taenia ovis""Molecular and Biochemical Parasitology2001pp. 173-181
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4. Sciutto, Edda; Fragoso, Gladis; Manoutcharian, Karen; Gevorkian, Goar; Rosas-Salgado, Gabriela; Hernandez-Gonzalez, Marisela; Herrera-Estrella, Luis; Cabrera-Ponce, Jose Luis; Lopez-Casillas, Fernando; Gonzalez-Bonilla, Cesar; Santiago-Machuca, Araceli; Ruiz-Perez, Fernando; Sanchez, Joaquin; Goldbaum, Fernando; Aluja, Aline; Larralde, Carlos,""New Approaches to Improve a Peptide Vaccine Against Porcine Taenia solium Cysticercosis""Archives of Medical Research2002pp. 371-378
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5. Wang, Qing-min; Sun, Shu-han; Hu, Zhen-lin; Wu, Dan; Wang, Zhong-chuan,""Immune response and protection elicited by DNA immunisation against Taenia cysticercosis""Vaccine2003pp. 1672-1680
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6. Ito, Akira; Urbani, Carlo; Jiamin, Qiu; Vuitton, Dominique A.; Dongchuan, Qiu; Heath, David D.; Craig, Philip S.; Zheng, Feng; Schantz, Peter M.,""Control of echinococcosis and cysticercosis: a public health challenge to international cooperation in China""Acta Tropica2003pp. 3-17
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7. Gonzalez, Armando E.; Garcia, H.H.; Gilman, Robert H.; Tsang, Victor C.W.,""Control of Taenia solium""Acta Tropica2003pp. 103-109
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8. Lightowlers, M.W.,""Vaccines for prevention of cysticercosis""Acta Tropica2003pp. 129-135
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9. Engels, Dirk; Urbani, Carlo; Belotto, Albino; Meslin, Francois; Savioli, Lorenzo,""The control of human (neuro)cysticercosis: which way forward?""Acta Tropica2003pp. 177-182
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10. Lightowlers, M.W.; Colebrook, A.L.; Gauci, C.G.; Gauci, S.M.; Kyngdon, C.T.; Monkhouse, J.L.; Vallejo Rodriquez, C.; Read, A.J.; Rolfe, R.A.; Sato, C.,""Vaccination against cestode parasites: anti-helminth vaccines that work and why""Veterinary Parasitology2003pp. 83-123
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11. Lightowlers, M.W.; Gauci, C.G.; Chow, C.; Drew, D.R.; Gauci, S.M.; Heath, D.D.; Jackson, D.C.; Dadley-Moore, D.L.; Read, A.J.,""Molecular and genetic characterisation of the host-protective oncosphere antigens of taeniid cestode parasites""International Journal for Parasitology2003pp. 1207-1217
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12. Sciutto, E.; Martinez, J.J.; Huerta, M.; Avila, R.; Fragoso, G.; Villalobos, N.; de Aluja, A.; Larralde, C.,""Familial clustering of Taenia solium cysticercosis in the rural pigs of Mexico: hints of genetic determinants in innate and acquired resistance to infection""Veterinary Parasitology2003pp. 223-229
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13. Sciutto, Edda; Fragoso, Gladis; Fleury, Agnes; Laclette, Juan Pedro; Sotelo, Julio; Aluja, Aline; Vargas, Laura; Larralde, Carlos,""Taenia solium disease in humans and pigs: an ancient parasitosis disease rooted in developing countries and emerging as a major health problem of global dimensions""Microbes and Infection2000pp. 1875-1890
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14. Hagan, P.; Doenhoff, M.J.; Wilson, R.A.; Al-Sherbiny, M.; Bergquist, R.,""Schistosomiasis Vaccines: A Response to a Devils' Advocate's View¹""Parasitology Today2000pp. 322-323
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Footnotes:

1. NB see Letters, this issue.