is an important cause of human morbidity and mortality, particularly in Latin America and parts of Africa and Asia. The disease has been recognised as potentially eradicable. Emphasis has been placed on control of the parasite through
s chemotherapy of human populations to remove tapeworm carriers. This strategy does not control the source of tapeworm infections, cysticercosis in pigs, and parasite transmission may continue due to incomplete chemotherapy coverage of human tapeworm carriers or because of immigration of tapeworm carriers into control areas. Exceptionally effective, practical vaccines have been developed against cysticercosis in sheep and cattle and a recent trial has proved recombinant antigens to be effective against
cysticercosis in pigs. A new strategy for eradication of
is proposed, based principally on a combined approach of chemotherapy of human tapeworm carriers and vaccination of all pigs at risk of infection.
Cited by: | - Lightowlers, Marshall W.; Gauci, Charles G.,""Vaccines against cysticercosis and hydatidosis""Veterinary Parasitology2001pp. 337-352
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vacp avtwaw"">Bibliographic Pagevacpavtwaw&form=pdf&file=file.pdf"">Full TextLightowlers, M.W.; Gauci, C.G.; Chow, C.; Drew, D.R.; Gauci, S.M.; Heath, D.D.; Jackson, D.C.; Dadley-Moore, D.L.; Read, A.J.,""Molecular and genetic characterisation of the host-protective oncosphere antigens of taeniid cestode parasites""International Journal for Parasitology2003pp. 1207-1217 Bibliographic PageFull TextSciutto, E.; Martinez, J.J.; Huerta, M.; Avila, R.; Fragoso, G.; Villalobos, N.; de Aluja, A.; Larralde, C.,""Familial clustering of Taenia solium cysticercosis in the rural pigs of Mexico: hints of genetic determinants in innate and acquired resistance to infection""Veterinary Parasitology2003pp. 223-229 Bibliographic PageFull TextSciutto, Edda; Fragoso, Gladis; Fleury, Agnes; Laclette, Juan Pedro; Sotelo, Julio; Aluja, Aline; Vargas, Laura; Larralde, Carlos,""Taenia solium disease in humans and pigs: an ancient parasitosis disease rooted in developing countries and emerging as a major health problem of global dimensions""Microbes and Infection2000pp. 1875-1890 Bibliographic PageFull TextHagan, P.; Doenhoff, M.J.; Wilson, R.A.; Al-Sherbiny, M.; Bergquist, R.,""Schistosomiasis Vaccines: A Response to a Devils' Advocate's View1""Parasitology Today2000pp. 322-323 Bibliographic PageFull Text |