Maternal risk factors for abnormal vaginal flora during pregnancy

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• 作者：Cecilia Tibaldi^a ; ^{ceciliatibaldi@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; Nazario Cappello^b ; Maria A. Latino^c ; Giulia Polarolo^a ; Giulia Masuelli^a ; Franco Cavallo^b ; Chiara Benedetto^a
• 关键词：Bacterial vaginosis ; Pregnancy ; Sexual behavior ; Sexually transmitted infection ; Vaginal flora
• 刊名：International Journal of Gynecology and Obstetrics
• 出版年：2016
• 出版时间：April 2016
• 年：2016
• 卷：133
• 期：1
• 页码：89-93
• 全文大小：339 K

文摘

To determine the prevalence of abnormal vaginal flora during pregnancy and associated maternal risk factors.

Methods

A retrospective study was undertaken of cervicovaginal smears performed on pregnant women at a center in Turin, Italy, between 2000 and 2010. Patients were divided into three groups: women with symptoms of genital infections (G1), asymptomatic women at risk of preterm birth (G2), and asymptomatic women with no risk (G3). Logistic regression models identified variables associated with microorganisms.

Results

Among 11 219 samples, 4913 (43.8%) were positive, of which 3783 (77.0%) were positive for a single microorganism. Multivariate analysis for G1 showed positive associations between multiple sexual partners and bacterial vaginosis/Ureaplasma urealyticum, and multiparity with preterm birth and U. urealyticum (P < 0.05 for all). In G2, there were significant associations between multiparity with preterm birth and bacterial vaginosis/aerobic vaginitis, and North African origin and bacterial vaginosis/U. urealyticum (P < 0.05 for all). In G3, there were associations between little education (< 8 years) and bacterial vaginosis/U. urealyticum, multiple sexual partners and bacterial vaginosis/U. urealyticum, and bacterial vaginosis and Eastern European origin and not being married (P < 0.05 for all).

Conclusion

Positive cervicovaginal smears were associated with a particular profile. Testing could be advisable for symptomatic women at any stage of pregnancy, during the first trimester for asymptomatic women at risk of preterm birth, and for some asymptomatic women.