Effect of a human serotonin 5-HT2A receptor gene polymorphism on impulsivity: Dependence on cholesterol levels
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- 作者：Katrin Tomsona ; b ; katrin.tomson@ut.ee" class="auth_mail" title="E-mail the corresponding author ; Mariliis Vahta ; mariliis.vaht@ut.ee" class="auth_mail" title="E-mail the corresponding author ; Kariina Laasa ; kariina.laas@ut.ee" class="auth_mail" title="E-mail the corresponding author ; Toomas Veidebaumc ; toomas.veidebaum@tai.ee" class="auth_mail" title="E-mail the corresponding author ; Jaanus Harroa ; jaanus.harro@ut.ee" class="auth_mail" title="E-mail the corresponding author
- 关键词：Maladaptive Impulsivity ; HTR2A ; LDL ; Gender
- 刊名：Journal of Affective Disorders
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：206
- 期：Complete
- 页码：23-30
- 全文大小：472 K
文摘
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Impulsivity is related to serotonergic mechanisms, but has distinct components.
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HTR2A -1438A/G polymorphism is associated with maladaptive impulsivity.
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This genotype effect is dependent on total and LDL cholesterol levels.
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HTR2A genotype and cholesterol effects on impulsivity differ in males and females.