Usefulness of toxicological validation of VOCs catalytic degradation by air-liquid interface exposure system

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• 作者：Margueritta Al Zallouha ; Yann Landkocz ; Julien Brunet ; Renaud Cousin ; Eric Genty ; Dominique Courcot ; Sté ; phane Siffert ; Pirouz Shirali ; Sylvain Billet ; ^{Sylvain.Billet@univ-littoral.fr}
• 关键词：Catalytic oxidation ; Air-liquid interface exposure ; Toluene ; Toxicological validation ; By-products identification
• 刊名：Environmental Research
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：152
• 期：Complete
• 页码：328-335
• 全文大小：601 K
• 卷排序：152

文摘

Catalytic oxidation is an efficient remediation technique of industrial VOC emissions Catalyst performance is generally assessed measuring VOC conversion or CO2 emission, but not the formation of by-products. Untargeted toxicological validation of catalyst by coupling it to an Air-Liquid Interface exposure system. Using biological system allows integrating synergy and antagonism in toxic effects of emitted VOCs and by-products. CYP1A1 induction in exposed A549 cells showed the formation of PAHs undetected by chemical methods.